Stuff, that really really hurts with U

• Ulcer

  Painful sore in stomach or mouth, can really ache.

• Uppercut

  Punch to the chin, classic boxing blow that hurts.

• Underwear wedgie

  Classic prank that really stings your backside.

• urinary tract infection

  UTI causes burning urination and pelvic pain.

• Upset stomach

  Cramping, nausea, can be seriously painful.

• Underarm waxing

  Ripping hair from skin, sharp stinging pain.

• Upchucking

  Vomiting hard; throat, belly and chest can burn.

• Umbrella to the face

  A smack from an umbrella can really sting!

• uranium

  Highly radioactive; causes deadly damage

• Uppercuts

  Punch to the chin/jaw, serious physical pain

The words in the list Stuff, that really really hurts with U come from players of the word game City, Country, River.